Prospects for the development of solid dispersed systems of antibiotics (scoping review)

Introduction. Currently, there is a large number of antibacterial medications for the treatment infectious diseases on pharmaceutical market. Fluoroquinolones, being an important group among these medications, have wide spectrum action and are active against multiresistant bacteria, one which ofloxacin. Ofloxacin characterized by low solubility belongs to second class according biopharmaceutical classification so it advisable use method introducing into solid carriers increase bioavailability. Purpose article describe methods obtaining new dosage forms ofloxacin with increased Materials : Having analyzed literature topic, authors presented brief description techniques manufacture dispersions this substance. Results conclusion The effect other excipients, such as surfactants, release medication from formulation has been described. physicochemical that can be used establish quality newly developed form reflected. Using described in article, possible create improved performance relation existing This will allow creation prolonged drug fewer side effects more profitable economic terms.